RAD54L2 and POU1F1

Data Source:
BioGRID (two hybrid)

		RAD54L2	POU1F1
Description		RAD54 like 2	POU class 1 homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding DNA Helicase Activity Protein Binding ATP Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Duplex Unwinding	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Adenohypophysis Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases			Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS		Estimated glomerular filtration rate ( 31152163)	Menarche (age at onset) ( 25231870) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		40 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 FAM118B HMG20A HNRNPCL1 HOMER1 IMPDH1 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A	22 interacting genes: ARID5A ARSA CREBBP ETS1 GATA2 JUN KRTAP10-8 KRTAP15-1 KRTAP6-1 LASP1 LHX4 MSX2 NCOR1 NR1I2 NR1I3 NR3C1 PITX1 PPARA PPARG RAD54L2 UBE2I VDR
Entrez ID		23132	5449
HPRD ID		10018	01409
Ensembl ID		ENSG00000164080	ENSG00000064835
Uniprot IDs		B3KV54 Q9Y4B4	P28069
PDB IDs			5WC9
Enriched GO Terms of Interacting Partners?
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