IMPDH2 and CPLANE2

Data Source:
BioGRID (two hybrid)

		IMPDH2	CPLANE2
Description		inosine monophosphate dehydrogenase 2	ciliogenesis and planar polarity effector 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Ciliary Basal Body
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation	Exocytosis Protein Transport Regulation Of Exocytosis Regulation Of Vesicle Fusion Cellular Protein Localization Cilium Assembly
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-carboxyamide-adenine dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		15 interacting genes: AGR2 AKT1 ANKRD9 APIP CLK1 CPLANE2 IL1F10 IMPDH1 PIAS4 POU6F2 STAT3 SUMO2 SUMO4 TRAF2 UBQLN4	5 interacting genes: FUZ IMPDH2 MSLN RND3 TMEM14C
Entrez ID		3615	79363
HPRD ID		00895	14399
Ensembl ID		ENSG00000178035	ENSG00000132881
Uniprot IDs		A0A384N6C2 P12268	Q9BU20
PDB IDs		1B3O 1NF7 1NFB 6I0M 6I0O 6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO 6UDP 6UDQ
Enriched GO Terms of Interacting Partners?
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