KRT26 and KRT6A

Data Source:
BioGRID (two hybrid)

		KRT26	KRT6A
Description		keratin 26	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Keratinization Cornification	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Asthma ( 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		23 interacting genes: BLOC1S2 CCDC146 FAM86C1P HGS KIFC3 KRT1 KRT3 KRT6A KRT6C KRT71 KRT74 KRT75 KRT81 KRT85 MCCD1 SLC19A1 SNAPIN SUOX TRIB3 TXLNB UCHL5 USHBP1 WASHC1	38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		353288	3853
HPRD ID		17243	01011
Ensembl ID		ENSG00000186393	ENSG00000205420
Uniprot IDs		Q7Z3Y9	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?
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