LCE1E and ZCCHC7

Data Source:
BioGRID (two hybrid)

		LCE1E	ZCCHC7
Description		late cornified envelope 1E	zinc finger CCHC-type containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleolus Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Keratinization
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Inflammatory skin disease ( 25574825)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Bitter beverage consumption ( 31046077) Chronotype ( 30696823) HIV-1 susceptibility ( 25786224) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite risk score for predicting weight gain ( 31560688) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)
Interacting Genes		59 interacting genes: ALPP CATSPER1 CYSRT1 EFEMP2 FAM9A FUCA2 GRN KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2B LCE2C LCE3B LCE4A LCE5A MACO1 MEOX2 NBPF19 NOTCH2NLA NTAQ1 PIAS2 RGS17 RNF4 SMCP TGM1 TRIM42 ZCCHC7	13 interacting genes: CARD9 CREBBP GIPC2 KIF9 LCE1E NEK6 PHC1 SNIP1 SUMO1 SUMO2 TRIM41 UBE2I ZNF250
Entrez ID		353135	84186
HPRD ID		13969	15703
Ensembl ID		ENSG00000186226	ENSG00000147905
Uniprot IDs		Q5T753	Q05DN1 Q8N3Z6
PDB IDs
Enriched GO Terms of Interacting Partners?
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