LCE1E and FUCA2

Data Source:
BioGRID (two hybrid)

		LCE1E	FUCA2
Description		late cornified envelope 1E	alpha-L-fucosidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Alpha-L-fucosidase Activity Protein Binding
	Biological Process	Keratinization	Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Formation of the cornified envelope	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Asthma ( 31619474) Inflammatory skin disease ( 25574825)	Multiple sclerosis ( 31604244)
Interacting Genes		59 interacting genes: ALPP CATSPER1 CYSRT1 EFEMP2 FAM9A FUCA2 GRN KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2B LCE2C LCE3B LCE4A LCE5A MACO1 MEOX2 NBPF19 NOTCH2NLA NTAQ1 PIAS2 RGS17 RNF4 SMCP TGM1 TRIM42 ZCCHC7	18 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 PIN1 TNPO2 VWC2 WNT11
Entrez ID		353135	2519
HPRD ID		13969	00649
Ensembl ID		ENSG00000186226	ENSG00000001036
Uniprot IDs		Q5T753	Q9BTY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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