IGH and FBXO2

Data Source:
BioGRID (pull down)

		IGH	FBXO2
Description		immunoglobulin heavy locus	F-box protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Endoplasmic Reticulum Cytosol SCF Ubiquitin Ligase Complex Organelle Membrane Dendritic Spine
	Molecular Function		Amyloid-beta Binding Ubiquitin-protein Transferase Activity Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Polyubiquitination Cellular Protein Modification Process Proteolysis Glycoprotein Catabolic Process Negative Regulation Of Cell Population Proliferation Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737) Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG monosialylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392)
Interacting Genes		2 interacting genes: FBXO2 NR1I3	16 interacting genes: AHSG BACE1 BRAP ECPAS IGH ITGB1 PAX4 PFDN6 SKP1 STUB1 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3 VSTM1
Entrez ID		3492	26232
HPRD ID			06171
Ensembl ID			ENSG00000116661
Uniprot IDs			Q9UK22
PDB IDs
Enriched GO Terms of Interacting Partners?
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