FBXO2 and ECPAS

Data Source:
BioGRID (two hybrid)

		FBXO2	ECPAS
Description		F-box protein 2	Ecm29 proteasome adaptor and scaffold
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol SCF Ubiquitin Ligase Complex Organelle Membrane Dendritic Spine	Proteasome Complex Nucleus Nucleoplasm Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Amyloid-beta Binding Ubiquitin-protein Transferase Activity Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	Protein Polyubiquitination Cellular Protein Modification Process Proteolysis Glycoprotein Catabolic Process Negative Regulation Of Cell Population Proliferation Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Post-translational Protein Modification	Ubiquitin-dependent ERAD Pathway Proteasome Assembly
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: AHSG BACE1 BRAP ECPAS IGH ITGB1 PAX4 PFDN6 SKP1 STUB1 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3 VSTM1	36 interacting genes: AGTRAP ANK2 ANKRD17 BSND CCDC57 CEP170B CKS1B CMTM5 CMTM6 CPD DGAT2L6 DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSD17B13 HSPB1 MAL2 MKI67 MYH10 PCM1 PCYT1B PSMC3 RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 TNFRSF10D UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		26232	23392
HPRD ID		06171	11078
Ensembl ID		ENSG00000116661	ENSG00000136813
Uniprot IDs		Q9UK22
PDB IDs
Enriched GO Terms of Interacting Partners?
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