ID3 and ZNF626

Data Source:
BioGRID (two hybrid)

		ID3	ZNF626
Description		inhibitor of DNA binding 3, HLH protein	zinc finger protein 626
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Dimerization Activity Transcription Regulator Activity Transcription Regulator Inhibitor Activity Leptomycin B Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Multicellular Organism Development Central Nervous System Development Heart Development Muscle Organ Development Response To Wounding Positive Regulation Of Gene Expression Cell Differentiation Neuron Differentiation Epithelial Cell Differentiation Notochord Development Circadian Regulation Of Gene Expression Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Cellular Response To Leptomycin B	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II
Pathways		NGF-stimulated transcription	Generic Transcription Pathway
Drugs
Diseases
GWAS			Cognitive decline (age-related) ( 28078323) Night sleep phenotypes ( 27126917) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		49 interacting genes: ADD1 ANKS1A ATF3 BOLA2 BOLA2B C22orf39 CBFA2T2 CDK2 CNOT3 CREB5 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 FRS3 GATA4 GNB2 GTF2A1L GUCD1 HES1 HOXA1 ID4 IFI16 IKBKG KAT5 KRTAP26-1 LMO4 MLX MSGN1 MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SDCBP SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626	2 interacting genes: FHL2 ID3
Entrez ID		3399	199777
HPRD ID		02608	15881
Ensembl ID		ENSG00000117318	ENSG00000188171
Uniprot IDs		Q02535	Q68DY1
PDB IDs		2LFH
Enriched GO Terms of Interacting Partners?
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