GFUS and RIOK2

Data Source:
BioGRID (two hybrid)

		GFUS	RIOK2
Description		GDP-L-fucose synthase	RIO kinase 2
Image
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Preribosome, Small Subunit Precursor
	Molecular Function	Protein Binding Electron Transfer Activity GDP-4-dehydro-D-rhamnose Reductase Activity Identical Protein Binding GDP-mannose 3,5-epimerase Activity GDP-L-fucose Synthase Activity	Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Leukocyte Cell-cell Adhesion Positive Regulation Of Endothelial Cell Migration GDP-mannose Metabolic Process Electron Transport Chain 'de Novo' GDP-L-fucose Biosynthetic Process Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin	Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Protein Autophosphorylation Positive Regulation Of Ribosomal Small Subunit Export From Nucleus Positive Regulation Of RRNA Processing
Pathways		GDP-fucose biosynthesis	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		NADH	Fostamatinib
Diseases
GWAS			Chronic mountain sickness ( 31417607) Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: ID2 NEDD4 RIOK2 UBC	7 interacting genes: APP CSNK2A1 GFUS PRDM16 RELA RPRD1A SMAD3
Entrez ID		7264	55781
HPRD ID		00654	10193
Ensembl ID		ENSG00000104522	ENSG00000058729
Uniprot IDs		A0A140VKC8 Q13630	Q9BVS4
PDB IDs		4B8W 4B8Z 4BKP 4BL5 4E5Y	5DHF 6FDM 6FDN 6FDO 6G18 6G51 6HK6
Enriched GO Terms of Interacting Partners?
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