HPR and PSKH1

Data Source:
HPRD (in vitro)

		HPR	PSKH1
Description		haptoglobin-related protein	protein serine kinase H1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Spherical High-density Lipoprotein Particle Extracellular Exosome Blood Microparticle	Endoplasmic Reticulum Membrane Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Nuclear Speck
	Molecular Function	Serine-type Endopeptidase Activity Hemoglobin Binding	Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Acute Inflammatory Response Receptor-mediated Endocytosis Positive Regulation Of Cell Death Zymogen Activation	Protein Phosphorylation Determination Of Left/right Symmetry Heart Development
Pathways		Scavenging of heme from plasma
Drugs		Zinc Copper Zinc acetate
Diseases
GWAS		Blood protein levels ( 28240269) Cholesterol, total ( 24097068 28270201 25961943 20686565 26582766) Coronary artery disease ( 32469254 33020668) Hematocrit ( 32888494) LDL cholesterol ( 24097068 25961943 20686565 26582766) LDL cholesterol levels ( 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Liver enzyme levels (alkaline phosphatase) ( 22001757) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 22916037) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Total cholesterol levels ( 28334899) Triglyceride levels ( 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		3 interacting genes: APOA1 IGHM VKORC1	3 interacting genes: CDC6 RDH13 SNTA1
Entrez ID		3250	5681
HPRD ID		00773	01511
Ensembl ID		ENSG00000261701	ENSG00000159792
Uniprot IDs		P00739	P11801
PDB IDs
Enriched GO Terms of Interacting Partners?
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