HPR and APOA1

  • Data Source:
  • HPRD (in vitro)

HPR

APOA1

Description haptoglobin-related protein apolipoprotein A1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Cholesterol, total ( 24097068 28270201 25961943 20686565 26582766)
  • Coronary artery disease ( 32469254 33020668)
  • Hematocrit ( 32888494)
  • LDL cholesterol ( 24097068 25961943 20686565 26582766)
  • LDL cholesterol levels ( 28334899 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Liver enzyme levels (alkaline phosphatase) ( 22001757)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Metabolite levels ( 22916037)
  • Serum metabolite levels ( 31636271)
  • Serum metabolite levels (CMS) ( 31636271)
  • Total cholesterol levels ( 28334899)
  • Triglyceride levels ( 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes 3 interacting genes: APOA1 IGHM VKORC1 38 interacting genes: ABCA1 ABCA13 AKT2 APOA2 APOB APOC1 APOF APOL1 APP ATP5F1B BRAP CETP CFHR1 CLEC4G CMTM5 FBLN1 GPLD1 HP HPR JAK3 LBP LCAT MAP7D1 NAXE NDRG1 PCMT1 PDE1A PLTP POLR1H PON1 SAA2 SCARB1 SPP1 TNFRSF10C TOMM20 TREM2 TTR VKORC1
Entrez ID 3250 335
HPRD ID 00773 02517
Ensembl ID ENSG00000261701 ENSG00000118137
Uniprot IDs P00739 A0A024R3E3 P02647
PDB IDs 1AV1 1GW3 1GW4 1ODP 1ODQ 1ODR 2MSC 2MSD 2MSE 2N5E 3K2S 3R2P 4V6M 6CC9 6CCH 6CCX 6CLZ 6CM1 6PTS 6PTW 6W4E 6W4F
Enriched GO Terms of Interacting Partners?
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