HPR

Description		haptoglobin-related protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Spherical High-density Lipoprotein Particle Extracellular Exosome Blood Microparticle
	Molecular Function	Serine-type Endopeptidase Activity Hemoglobin Binding
	Biological Process	Acute Inflammatory Response Receptor-mediated Endocytosis Positive Regulation Of Cell Death Zymogen Activation
Pathways		Scavenging of heme from plasma
Drugs		Zinc Copper Zinc acetate
Diseases
GWAS		Blood protein levels ( 28240269) Cholesterol, total ( 24097068 28270201 25961943 20686565 26582766) Coronary artery disease ( 32469254 33020668) Hematocrit ( 32888494) LDL cholesterol ( 24097068 25961943 20686565 26582766) LDL cholesterol levels ( 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Liver enzyme levels (alkaline phosphatase) ( 22001757) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 22916037) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Total cholesterol levels ( 28334899) Triglyceride levels ( 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Novel Interacting Genes		2 novel interacting genes: DYNC1LI2 PSKH1
Interacting Genes		3 interacting genes: APOA1 IGHM VKORC1
Entrez ID		3250
HPRD ID		00773
Ensembl ID		ENSG00000261701
Uniprot IDs		P00739
PDB IDs
Enriched GO Terms of Interacting Partners?
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