HOXC9 and IRF9

Data Source:
BioGRID (two hybrid)

		HOXC9	IRF9
Description		homeobox C9	interferon regulatory factor 9
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis	Immune System Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways			Interferon gamma signaling Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 TEX37 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384	19 interacting genes: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX
Entrez ID		3225	10379
HPRD ID		00857	00960
Ensembl ID		ENSG00000180806	ENSG00000213928
Uniprot IDs		A0A024RAZ6 P31274	Q00978
PDB IDs		2LP0 2MSY
Enriched GO Terms of Interacting Partners?
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