IRF9 and HOXC9

Data Source:
BioGRID (two hybrid)

		IRF9	HOXC9
Description		interferon regulatory factor 9	homeobox C9
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Aggresome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis
Pathways		Interferon gamma signaling Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		19 interacting genes: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX	29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 TEX37 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384
Entrez ID		10379	3225
HPRD ID		00960	00857
Ensembl ID		ENSG00000213928	ENSG00000180806
Uniprot IDs		Q00978	A0A024RAZ6 P31274
PDB IDs			2LP0 2MSY
Enriched GO Terms of Interacting Partners?
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