NCBP1 and NCBP3

Data Source:
BioGRID (two hybrid)

		NCBP1	NCBP3
Description		nuclear cap binding protein subunit 1	nuclear cap binding subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Cytosol MRNA Cap Binding Complex Nuclear Cap Binding Complex RNA Cap Binding Complex Ribonucleoprotein Complex	Nucleus Cytoplasm Nuclear Speck RNA Cap Binding Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription 7-methylguanosine MRNA Capping RNA Catabolic Process RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translational Initiation Histone MRNA Metabolic Process RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Positive Regulation Of Cell Growth Gene Silencing By RNA MRNA 3'-end Processing Positive Regulation Of MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II MRNA Cis Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nuclear Export Pre-mRNA Cleavage Required For Polyadenylation Regulation Of MRNA Polyadenylation Positive Regulation Of RNA Binding	7-methylguanosine MRNA Capping MRNA Transport Defense Response To Virus
Pathways		SLBP independent Processing of Histone Pre-mRNAs Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Abortive elongation of HIV-1 transcript in the absence of Tat snRNP Assembly RNA Polymerase II Pre-transcription Events FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Intronless Pre-mRNAs Signaling by FGFR2 IIIa TM Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes		18 interacting genes: BNIP1 BNIP2 BNIP3 EIF4G1 EIF4G2 HNRNPF HNRNPH1 LINC01554 NCBP2 NCBP3 PSTPIP1 PTEN RNF20 RNF40 RPS6KB1 SNRPA1 STAU1 ZDHHC17	9 interacting genes: APP DAPK1 HMGB2 HNRNPH3 KPNA4 LENG8 LRRK2 NCBP1 SRPK2
Entrez ID		4686	55421
HPRD ID		02717	17116
Ensembl ID		ENSG00000136937	ENSG00000074356
Uniprot IDs		A0A024R179 Q09161	Q53F19
PDB IDs		1H2T 1H2U 1H2V 1H6K 1N52 1N54 3FEX 3FEY 5OO6 5OOB 6D0Y
Enriched GO Terms of Interacting Partners?
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