HLA-DMB and HLA-DOB

Data Source:
HPRD (in vivo)

		HLA-DMB	HLA-DOB
Description		major histocompatibility complex, class II, DM beta	major histocompatibility complex, class II, DO beta
Image
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex Intracellular Membrane-bounded Organelle	Lysosome Lysosomal Membrane Endosome Membrane Integral Component Of Membrane MHC Class II Protein Complex
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding	MHC Class II Protein Complex Binding MHC Class II Receptor Activity
	Biological Process	Adaptive Immune Response MHC Class II Protein Complex Assembly Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell	Adaptive Immune Response Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		MHC class II antigen presentation	MHC class II antigen presentation
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Dermatomyositis ( 27153935) Lung cancer ( 28604730) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Schizophrenia ( 30285260) Squamous cell lung carcinoma ( 28604730)	Asthma ( 31619474) Asthma and major depressive disorder ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 23266558) Kawasaki disease ( 33106546 22446962) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 30285260) Squamous cell lung carcinoma ( 28604730) Takayasu arteritis ( 25604533) Type 2 diabetes ( 30054458)
Interacting Genes		11 interacting genes: CD63 CD74 CD82 CUL3 DPM2 HLA-DMA HLA-DOB HLA-DRA MDM2 PSEN2 TEAD1	2 interacting genes: CDKN2A HLA-DMB
Entrez ID		3109	3112
HPRD ID		00831	08368
Ensembl ID		ENSG00000242574	ENSG00000241106
Uniprot IDs		A0A1V0E3P2 P28068	P13765 Q5QNS2
PDB IDs		1HDM 2BC4 4FQX 4GBX 4I0P	4I0P
Enriched GO Terms of Interacting Partners?
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