HLA-DMB and HLA-DMA

Data Source:
HPRD (in vivo)

		HLA-DMB	HLA-DMA
Description		major histocompatibility complex, class II, DM beta	major histocompatibility complex, class II, DM alpha
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GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex Intracellular Membrane-bounded Organelle	Lysosomal Membrane Cell Surface Membrane Integral Component Of Membrane Late Endosome Membrane MHC Class II Protein Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding	Protein Binding MHC Class II Protein Complex Binding
	Biological Process	Adaptive Immune Response MHC Class II Protein Complex Assembly Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell	Adaptive Immune Response Peptide Antigen Assembly With MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		MHC class II antigen presentation
Drugs
Diseases			Allograft rejection
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Dermatomyositis ( 27153935) Lung cancer ( 28604730) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Schizophrenia ( 30285260) Squamous cell lung carcinoma ( 28604730)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)
Interacting Genes		11 interacting genes: CD63 CD74 CD82 CUL3 DPM2 HLA-DMA HLA-DOB HLA-DRA MDM2 PSEN2 TEAD1	8 interacting genes: B3GAT1 CD74 CD82 HLA-DMB HLA-DOA HLA-DRA HLA-DRB1 U2AF2
Entrez ID		3109	3108
HPRD ID		00831	00830
Ensembl ID		ENSG00000242574	ENSG00000204257
Uniprot IDs		A0A1V0E3P2 P28068	Q31604 Q6ICR9
PDB IDs		1HDM 2BC4 4FQX 4GBX 4I0P	4I0P
Enriched GO Terms of Interacting Partners?
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