SOCS7 and IRS4

		SOCS7	IRS4
Description		suppressor of cytokine signaling 7	insulin receptor substrate 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex	Cytosol Plasma Membrane
	Molecular Function	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding
	Biological Process	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation	Signal Transduction Insulin Receptor Signaling Pathway
Pathways			IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Interacting Genes		26 interacting genes: CYSRT1 DAB1 EGFR EXOSC8 GAS2L2 GRB2 HSPB8 IRS2 IRS4 LENG8 MDFI MISP NCK1 NCK2 NSMF OSTF1 PIK3R1 PIK3R2 PLCG1 SH3RF1 SORBS2 SORBS3 TNS2 TUBA1A TUBB4B YES1	22 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTEN PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG
Entrez ID		30837	8471
HPRD ID		12299	04620
Ensembl ID		ENSG00000274211	ENSG00000133124
Uniprot IDs		O14512	O14654
PDB IDs
Enriched GO Terms of Interacting Partners?
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