CD209 and ICAM3

Data Source:
HPRD (in vivo, in vitro)

		CD209	ICAM3
Description		CD209 molecule	intercellular adhesion molecule 3
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Host Cell	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding	Signaling Receptor Binding Integrin Binding Protein Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Process Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion Positive Regulation Of Viral Life Cycle	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion
Pathways		CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		9 interacting genes: CEACAM1 CLEC4M CLU ICAM2 ICAM3 IFT20 ITGAM TCEAL8 VAC14	20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16
Entrez ID		30835	3385
HPRD ID		05241	00889
Ensembl ID		ENSG00000090659	ENSG00000076662
Uniprot IDs		B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12	A0A024R7C1 K7ERN2 P32942
PDB IDs		1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV	1T0P
Enriched GO Terms of Interacting Partners?
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