HARS1 and EEF1G

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, in vivo)

		HARS1	EEF1G
Description		histidyl-tRNA synthetase 1	eukaryotic translation elongation factor 1 gamma
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome
	Molecular Function	Histidine-tRNA Ligase Activity ATP Binding Identical Protein Binding Protein Homodimerization Activity	Translation Elongation Factor Activity Protein Binding Cadherin Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Histidyl-tRNA Aminoacylation Mitochondrial Translation	Translational Elongation Glutathione Metabolic Process Response To Virus
Pathways		Cytosolic tRNA aminoacylation	Eukaryotic Translation Elongation
Drugs		Histidine
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		7 interacting genes: EEF1B2 EEF1G MTNR1B PSMC5 RPL5 TARS1 TNIK	93 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		3035	1937
HPRD ID		00827	11745
Ensembl ID		ENSG00000170445	ENSG00000254772
Uniprot IDs		B4DDD8 B4E1C5 P12081	P26641 Q53YD7
PDB IDs		1X59 2LW7 4G84 4G85 4PHC 4X5O 5W6M 6O76	1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?
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