EEF1G and ADAP2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1G	ADAP2
Description		eukaryotic translation elongation factor 1 gamma	ArfGAP with dual PH domains 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Cytoplasm Mitochondrial Envelope Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein-macromolecule Adaptor Activity Phosphatidylinositol-3,4-bisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding
	Biological Process	Translational Elongation Glutathione Metabolic Process Response To Virus	Heart Development Positive Regulation Of GTPase Activity Inositol Lipid-mediated Signaling
Pathways		Eukaryotic Translation Elongation
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Height ( 28552196) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		93 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	9 interacting genes: APP EEF1G IKBKG NCL NEDD4L PRNP RANBP9 SNCA TUBB
Entrez ID		1937	55803
HPRD ID		11745	16357
Ensembl ID		ENSG00000254772	ENSG00000184060
Uniprot IDs		P26641 Q53YD7	Q2V6Q1 Q9NPF8
PDB IDs		1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?
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