H2BC3 and EID1

Data Source:
BioGRID (pull down)

		H2BC3	EID1
Description		H2B clustered histone 3	EP300 interacting inhibitor of differentiation 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleosome Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	DNA Binding Protein Binding Protein Heterodimerization Activity	Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Regulator Activity Histone Acetyltransferase Binding
	Biological Process	Nucleosome Assembly Protein Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Cell Differentiation Regulation Of Histone Acetylation Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Pre-NOTCH Transcription and Translation Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex PRC2 methylates histones and DNA Condensation of Prophase Chromosomes Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) DNA Damage/Telomere Stress Induced Senescence HDACs deacetylate histones HATs acetylate histones HATs acetylate histones SIRT1 negatively regulates rRNA expression ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression NoRC negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression DNA methylation Transcriptional regulation by small RNAs Activation of anterior HOX genes in hindbrain development during early embryogenesis Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Ub-specific processing proteases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Deposition of new CENPA-containing nucleosomes at the centromere G2/M DNA damage checkpoint RNA Polymerase I Promoter Opening RNA Polymerase I Promoter Escape E3 ubiquitin ligases ubiquitinate target proteins RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Meiotic recombination HCMV Early Events HCMV Late Events Transcriptional regulation of granulopoiesis Inhibition of DNA recombination at telomere Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes		25 interacting genes: AKT1 APP CDK1 CDK2 CREBBP DYRK1A EID1 EP300 ERCC6 FANCD2 H2AC4 KAT2B MYB PALB2 PSMD4 RHBDD2 RNF20 RNF8 RPS6KA5 UBR7 UHRF1 USP16 USP36 USP43 USP51	18 interacting genes: ARID4A CREBBP EP300 H2AC8 H2BC3 H3C1 H4C1 KAT2A MDM2 NCOA2 NDN NR0B2 PCID2 PSEN2 RB1 TRIM27 UBE3A XRCC6
Entrez ID		3018	23741
HPRD ID		07536	06907
Ensembl ID		ENSG00000276410	ENSG00000255302
Uniprot IDs		P33778	Q9Y6B2
PDB IDs		3X1S 3X1U
Enriched GO Terms of Interacting Partners?
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