SERTAD3 and P4HA3

Data Source:
BioGRID (two hybrid)

		SERTAD3	P4HA3
Description		SERTA domain containing 3	prolyl 4-hydroxylase subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Hippocampal atrophy ( 25625606)
Interacting Genes		43 interacting genes: ANKRD11 BEX2 BFSP2 C1orf216 CCNC CENPP CREBBP CTNNAL1 DPPA3 FAAP20 FBXO44 FCHSD2 GTPBP3 HGS IL16 IMP3 KANK2 KLHL42 KPNA2 MBD3 MED25 MSGN1 NDN NPPB P4HA3 PICK1 PKN1 PRKAA2 RPA2 RTP5 SMARCD1 SNRPB SPG11 SUOX TASOR2 TLE5 TNPO2 TPRX1 TRAPPC6A TXN UBL5 USHBP1 ZGPAT	50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A
Entrez ID		29946	283208
HPRD ID		15327	16413
Ensembl ID		ENSG00000167565	ENSG00000149380
Uniprot IDs		A0A024R0N2 Q9UJW9	Q7Z4N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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