UBIAD1 and CRB3

Data Source:
BioGRID (two hybrid)

		UBIAD1	CRB3
Description		UbiA prenyltransferase domain containing 1	crumbs cell polarity complex component 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Golgi Membrane Mitochondrial Membrane	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Extracellular Exosome
	Molecular Function	Prenyltransferase Activity Protein Binding Antioxidant Activity	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	Ubiquinone Biosynthetic Process Menaquinone Biosynthetic Process Ubiquinone Biosynthetic Process Via 3,4-dihydroxy-5-polyprenylbenzoate Vitamin K Biosynthetic Process Vitamin K Metabolic Process Cellular Oxidant Detoxification	Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Positive Regulation Of Cell Junction Assembly
Pathways		Metabolism of vitamin K	Tight junction interactions
Drugs
Diseases		Schnyder corneal dystrophy (SCD); Schnyder crystalline corneal dystrophy (SCCD); Crystalline stromal dystrophy; Schnyder crystalline dystrophy sine crystals
GWAS		Beard thickness ( 26926045) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010) Weight ( 28552196)
Interacting Genes		38 interacting genes: AHNAK2 ASGR2 BIK CD33 CD53 CD79A CLDN7 CPLX4 CRB3 CREB3L1 CYB5R3 EBP ERGIC3 EVI2A EVI2B FAM209A FCER1G FKBP7 FNDC9 GPR152 HIBADH KCNJ6 LHFPL5 MGST3 MRM3 NCAPH2 PHACTR3 PIGP REEP4 RETREG3 SAR1A SCN3B SLC7A14 SYT1 TMEFF2 TMEM139 TMEM14B VEGFA	28 interacting genes: ANKRD46 BCL2L13 BET1 FUNDC2 HMOX1 HMOX2 NDUFA3 PALS1 PARD6A PATJ PLLP PLP2 PSENEN PSMA3 RABAC1 SERF1A SERF1B SERP1 SLC39A9 STX5 TECR TMEM222 TREX1 UBIAD1 VAMP1 VTI1B WDR83 YIPF6
Entrez ID		29914	92359
HPRD ID		15487	16749
Ensembl ID		ENSG00000120942	ENSG00000130545
Uniprot IDs		Q9Y5Z9	Q9BUF7
PDB IDs			5I7Z
Enriched GO Terms of Interacting Partners?
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