UBIAD1 and CYB5R3

Data Source:
BioGRID (two hybrid)

		UBIAD1	CYB5R3
Description		UbiA prenyltransferase domain containing 1	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Golgi Membrane Mitochondrial Membrane	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Prenyltransferase Activity Protein Binding Antioxidant Activity	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Ubiquinone Biosynthetic Process Menaquinone Biosynthetic Process Ubiquinone Biosynthetic Process Via 3,4-dihydroxy-5-polyprenylbenzoate Vitamin K Biosynthetic Process Vitamin K Metabolic Process Cellular Oxidant Detoxification	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation
Pathways		Metabolism of vitamin K	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases		Schnyder corneal dystrophy (SCD); Schnyder crystalline corneal dystrophy (SCCD); Crystalline stromal dystrophy; Schnyder crystalline dystrophy sine crystals	Methemoglobinemia
GWAS		Beard thickness ( 26926045) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010) Weight ( 28552196)	Initial pursuit acceleration ( 29064472)
Interacting Genes		38 interacting genes: AHNAK2 ASGR2 BIK CD33 CD53 CD79A CLDN7 CPLX4 CRB3 CREB3L1 CYB5R3 EBP ERGIC3 EVI2A EVI2B FAM209A FCER1G FKBP7 FNDC9 GPR152 HIBADH KCNJ6 LHFPL5 MGST3 MRM3 NCAPH2 PHACTR3 PIGP REEP4 RETREG3 SAR1A SCN3B SLC7A14 SYT1 TMEFF2 TMEM139 TMEM14B VEGFA	61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15
Entrez ID		29914	1727
HPRD ID		15487	08942
Ensembl ID		ENSG00000120942	ENSG00000100243
Uniprot IDs		Q9Y5Z9	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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