MSH6 and MAP2K1

  • Data Source:
  • BioGRID (two hybrid)

MSH6

MAP2K1

Description mutS homolog 6 mitogen-activated protein kinase kinase 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549)
  • Lifetime average cigarettes per day in chronic obstructive pulmonary disease ( 21685187)
  • Menopause (age at onset) ( 26414677)
  • Takayasu arteritis ( 25604533)
  • Tea consumption ( 31046077)
Interacting Genes 18 interacting genes: BARD1 BRCA1 CHAF1A CREBBP CSNK2A1 EP300 HRAS HUS1 MAP2K1 MSH2 MUTYH NANS PCNA PTEN RAD1 RAD9A SMC1A SUMO2 67 interacting genes: APC ARAF AURKA BANP BAX BIRC6 BMPR1A BRAF BUB1 CASP9 CDH1 CDK5 CDKN2A CPNE1 CPNE4 CTNNA1 EGFR ELK1 EP300 ERBB2 FBXW7 GRB10 HNRNPD HRAS KAT7 KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MBP MLH3 MSH6 MYC ODC1 PAK1 PARVA PDGFRL PEBP1 PEBP4 PIK3CA PLEKHF2 PLK3 PPARG PRKCI PRKCZ PTPRJ RAF1 RPS6KA2 RPS6KA4 SMAD2 SRC STK11 TCP11 TGFBR2 TLR2 TRAF3 TRAF6 TRIB1 UBE2I UBE2L3 WNK1
Entrez ID 2956 5604
HPRD ID 07202 01469
Ensembl ID ENSG00000116062 ENSG00000169032
Uniprot IDs P52701 Q3SWU9 A4QPA9 B4DFY5 H3BRW9 Q02750
PDB IDs 2GFU 2O8B 2O8C 2O8D 2O8E 2O8F 6OQM 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3W8Q 3WIG 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 4LMN 4MNE 4U7Z 4U80 4U81 5BX0 5EYM 5HZE 5YT3 6NYB 6PP9 6Q0J 6Q0T 6U2G 6X2P 6X2S 6X2X
Enriched GO Terms of Interacting Partners?
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