MAP2K1 and RPS6KA2

  • Data Source:
  • HPRD (in vitro)

MAP2K1

RPS6KA2

Description mitogen-activated protein kinase kinase 1 ribosomal protein S6 kinase A2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alzheimer's disease progression score ( 29860282)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Blood pressure (smoking interaction) ( 25189868)
  • Dental caries ( 23259602)
  • Inflammatory bowel disease ( 27569725 23128233)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Smooth-surface caries ( 24556642)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Waist circumference ( 28552196)
Interacting Genes 67 interacting genes: APC ARAF AURKA BANP BAX BIRC6 BMPR1A BRAF BUB1 CASP9 CDH1 CDK5 CDKN2A CPNE1 CPNE4 CTNNA1 EGFR ELK1 EP300 ERBB2 FBXW7 GRB10 HNRNPD HRAS KAT7 KSR1 KSR2 LAMTOR3 MAP3K4 MAP3K8 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP3 MBP MLH3 MSH6 MYC ODC1 PAK1 PARVA PDGFRL PEBP1 PEBP4 PIK3CA PLEKHF2 PLK3 PPARG PRKCI PRKCZ PTPRJ RAF1 RPS6KA2 RPS6KA4 SMAD2 SRC STK11 TCP11 TGFBR2 TLR2 TRAF3 TRAF6 TRIB1 UBE2I UBE2L3 WNK1 12 interacting genes: BAD CREB1 FLNC FOS JUN L1CAM MAGI1 MAP2K1 MAPK1 MAPK3 SHANK1 TP53
Entrez ID 5604 6196
HPRD ID 01469 03403
Ensembl ID ENSG00000169032 ENSG00000071242
Uniprot IDs A4QPA9 B4DFY5 H3BRW9 Q02750 B7Z3B5 Q15349 X5D337
PDB IDs 1S9J 2P55 3DV3 3DY7 3E8N 3EQB 3EQC 3EQD 3EQF 3EQG 3EQH 3EQI 3MBL 3ORN 3OS3 3PP1 3SLS 3V01 3V04 3VVH 3W8Q 3WIG 3ZLS 3ZLW 3ZLX 3ZLY 3ZM4 4AN2 4AN3 4AN9 4ANB 4ARK 4LMN 4MNE 4U7Z 4U80 4U81 5BX0 5EYM 5HZE 5YT3 6NYB 6PP9 6Q0J 6Q0T 6U2G 6X2P 6X2S 6X2X
Enriched GO Terms of Interacting Partners?
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