NR3C1 and SMARCA2

  • Data Source:
  • HPRD (in vivo)

NR3C1

SMARCA2

Description nuclear receptor subfamily 3 group C member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma (childhood onset) ( 27611488)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Brain morphology (MOSTest) ( 32665545)
  • Lead levels ( 26025379)
  • Lung function (FEV1) ( 30061609)
  • Lung function (FVC) ( 30061609)
  • Monobrow ( 27182965)
  • Neuritic plaque ( 31497858)
  • Nose size ( 27182965)
  • Parkinson's disease ( 26227905)
  • Superior frontal gyrus grey matter volume ( 25335168)
  • Systolic blood pressure ( 26969751)
  • Thyroid volume in Hashimoto’s thyroiditis ( 32019955)
Interacting Genes 160 interacting genes: ABCC1 ADA AR ARPC5 BAG1 C1orf94 CALM1 CALR CEBPA CEBPB CENPB CHD9 COPS6 CREB1 CREBBP DAP3 DAPK1 DCAF6 DDX54 DNMT3L DOCK3 DTD1 ECD EFHC2 EGFR EPB41L1 ETS1 ETS2 FAM161B FKBP4 FTH1 FYN GNB1 GNB2 GRIP1 H3C1 HDAC1 HDAC6 HMGB1 HMGB2 HMOX2 HNRNPA1 HNRNPU HSP90AA1 HSP90AB1 HSPA1A HSPD1 IDE IFNGR2 JUN KAT5 KDM5A KPNA2 KRTCAP3 LCK LPXN LRIF1 MAFF MAPK1 MAPK15 MAPK8 MDM2 MED1 MED14 MED25 MSX2 NCL NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NEDD4L NFKB1 NFKB2 NR0B1 NR0B2 NR1H3 NR2E3 NR2F2 NR2F6 NR3C2 NR4A1 NRIP1 NUP54 ONECUT1 OSGEP PBX1 PELP1 PIAS2 PML POLR1D POU1F1 POU2F1 POU2F2 PPARGC1A PRDX3 PRKACA PRKDC PRPF6 PSMC3IP PTGES3 PTMS RACK1 RAD54L2 RAD9A RAF1 RAN RARA RBM14 RELA RFPL2 RNF14 RXRB SFN SGTA SHKBP1 SLC25A4 SMAD3 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCD1 SMARCE1 SPIN2A SRA1 SRC STAT3 STAT5A STAT5B STRN3 STUB1 SUMO1 SUMO4 SVIL SYT1 TADA2A TBP TDG TGFB1I1 TMF1 TNS4 TP53 TRIM24 TRIM28 TSG101 TXN UBB UBE2I UBE2L3 WTIP YWHAH ZBTB16 ZBTB20 ZBTB3 ZBTB9 ZNF496 27 interacting genes: ACTL6A ACTL6B AR ARID1B BEND7 BRCA1 CEBPA ESR1 H3C1 HSPB1 KHDRBS1 MDM2 MDM4 MECP2 MYB MYC NR0B2 NR3C1 NR4A2 PHB PITX1 PRMT5 PRPF6 RAP1A SDCBP SIN3B SS18
Entrez ID 2908 6595
HPRD ID 00679 02483
Ensembl ID ENSG00000113580 ENSG00000080503
Uniprot IDs B7Z7I2 E5KQF5 E5KQF6 F1D8N4 P04150 B1ALF6 B4DNT1 B4DSC8 F6T8Q0 F6VDE0 P51531 Q56A76 Q8N9Q1
PDB IDs 1M2Z 1NHZ 1P93 3BQD 3CLD 3E7C 3H52 3K22 3K23 4CSJ 4HN5 4HN6 4LSJ 4MDD 4P6W 4P6X 4UDC 4UDD 5CBX 5CBY 5CBZ 5CC1 5E69 5E6A 5E6B 5E6C 5E6D 5EMC 5EMP 5EMQ 5G3J 5G5W 5NFP 5NFT 5UC3 5VA0 5VA7 6BQU 6CFN 6DXK 6EL6 6EL7 6EL9 2DAT 4QY4 5DKC 5DKH 6EG2 6EG3 6HAX 6HAY 6HAZ
Enriched GO Terms of Interacting Partners?
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