GIT1 and CCDC113

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GIT1	CCDC113
Description		GIT ArfGAP 1	coiled-coil domain containing 113
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Focal Adhesion Membrane Calyx Of Held	Axoneme Protein-containing Complex Centriolar Satellite Ciliary Basal Body
	Molecular Function	GTPase Activator Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding	Protein Binding
	Biological Process	Intramembranous Ossification Brain Development Locomotory Behavior Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cytokinesis Negative Regulation Of Interleukin-1 Beta Production Positive Regulation Of GTPase Activity Cell Redox Homeostasis Negative Regulation Of Glycolytic Process Ephrin Receptor Signaling Pathway Neuron Development Motor Learning Cellular Response To Lipopolysaccharide Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Inflammatory Response To Wounding Regulation Of Synaptic Vesicle Exocytosis	Cilium Assembly
Pathways		Ephrin signaling Ephrin signaling Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545)	Primary biliary cholangitis ( 28425483) Systemic lupus erythematosus ( 28714469)
Interacting Genes		52 interacting genes: ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CDC42 CENPU CEP126 CHD3 DDX24 EIF6 ENTR1 GIT2 GRB2 GRK2 GRK3 GRK5 GRK6 HAP1 HMOX2 HTT KIF1A LAMTOR5 LPXN LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG	6 interacting genes: GIT1 HAP1 HSF2BP IMMT PFN2 SMYD1
Entrez ID		28964	29070
HPRD ID		06577	07121
Ensembl ID		ENSG00000108262	ENSG00000103021
Uniprot IDs		Q59FC3 Q9Y2X7	Q9H0I3
PDB IDs
Enriched GO Terms of Interacting Partners?
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