SKA1 and FAM9C

Data Source:
BioGRID (two hybrid)

		SKA1	FAM9C
Description		spindle and kinetochore associated complex subunit 1	family with sequence similarity 9 member C
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle	Synaptonemal Complex
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Spermatid Development Meiotic Cell Cycle
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1	10 interacting genes: ABI2 BORCS6 NDC80 SKA1 SNAP29 SNAPC5 TEX12 TPM1 TPM3 TRIML2
Entrez ID		220134	171484
HPRD ID		12689	06507
Ensembl ID		ENSG00000154839	ENSG00000187268
Uniprot IDs		A0A024R294 Q96BD8	A0A024RBW5 Q8IZT9
PDB IDs		4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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