BRICD5 and SLC18A2

Data Source:
BioGRID (two hybrid)

		BRICD5	SLC18A2
Description		BRICHOS domain containing 5	solute carrier family 18 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse
	Molecular Function	Protein Binding	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Regulation Of Cell Population Proliferation	Response To Amphetamine Chemical Synaptic Transmission Neurotransmitter Secretion Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Sequestering Of Neurotransmitter Serotonin Uptake Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Na+/Cl- dependent neurotransmitter transporters
Drugs			Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS			Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925)
Interacting Genes		41 interacting genes: AQP6 ARL13B BIK CD69 CD79A CLEC2D CLRN1 CREB3L1 FKBP7 HHLA2 HSD17B13 ICAM3 IFNGR2 IFNLR1 IL27RA KIR2DL3 KLRC1 LMNA LRRC25 LRRC4C MRM1 MTIF3 MUC1 NEMP1 PLEKHO1 PSCA PVR SCN3B SGCB SGPL1 SIGLEC9 SLAMF6 SLC18A1 SLC18A2 SORT1 SYNE4 TMEM234 TMEM248 TMEM79 TMPRSS2 TMX2	14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 MFSD5 NKG7 SLC7A1 TMEM109 TOMM6
Entrez ID		283870	6571
HPRD ID		14482	01896
Ensembl ID		ENSG00000182685	ENSG00000165646
Uniprot IDs		Q6PL45	Q05940
PDB IDs
Enriched GO Terms of Interacting Partners?
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