GNAI1 and S1PR1

  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, two hybrid)
  • HPRD (in vitro, in vivo, two hybrid)

GNAI1

S1PR1

Description G protein subunit alpha i1 sphingosine-1-phosphate receptor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
  • Night sleep phenotypes ( 27126917)
  • Post bronchodilator FEV1 ( 26634245)
  • Irritable bowel syndrome ( 29673008)
  • Lymphocyte counts ( 29403010 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494)
  • Monocyte count ( 32888494)
  • Multiple sclerosis and C-reactive protein levels (pleiotropy) ( 26920376)
  • Multiple sclerosis and HDL levels (pleiotropy) ( 26920376)
  • Sensorimotor dexterity ( 31596458)
  • Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)
Interacting Genes 62 interacting genes: ADCY5 ADRA2A ADRB2 CCR5 CD47 CNR1 CRHR1 CXCR4 DRD3 DRD4 EPOR ESR1 FFAR1 GNAO1 GNB2 GNB4 GNG2 GPR1 GPR143 GPSM1 GPSM2 GPSM3 HRH4 HTR2A IGF1R KLHL3 MTNR1A MTNR1B NGB NUCB1 NUMA1 OPRD1 OPRM1 PCP2 PDE6D PTEN PTPRU RANGAP1 RASD1 RGS10 RGS12 RGS14 RGS16 RGS17 RGS18 RGS19 RGS20 RGS4 RGS7 RIC8A S1PR1 S1PR2 S1PR3 S1PR4 S1PR5 SSTR2 SSTR3 STRN THAP7 TSHR VIPR1 WASF1 9 interacting genes: AKT1 APP CAV1 CMSS1 GNAI1 GNAI3 HTR1A HTR1D PDGFRB
Entrez ID 2770 1901
HPRD ID 00756 03578
Ensembl ID ENSG00000127955 ENSG00000170989
Uniprot IDs P63096 P21453
PDB IDs 1KJY 1Y3A 2G83 2GTP 2IK8 2OM2 2XNS 3ONW 3QE0 3QI2 3UMR 3UMS 4G5Q 5JS7 5JS8 5TDH 6CMO 6CRK 6DDE 6DDF 6KPF 6KPG 6LFM 6LFO 6LML 6N4B 6OMM 6OS9 6OSA 6OT0 6PB0 6PB1 6PT0 6QNO 6VU8 6XBJ 6XBK 6XBL 6XBM 3V2W 3V2Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?