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GNA11 and EDNRB
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
GNA11
EDNRB
Description
G protein subunit alpha 11
endothelin receptor type B
Image
GO Annotations
Cellular Component
Photoreceptor Outer Segment
Cytoplasm
Lysosomal Membrane
Heterotrimeric G-protein Complex
Plasma Membrane
Synapse
Extracellular Exosome
Plasma Membrane
Integral Component Of Plasma Membrane
Nuclear Membrane
Membrane Raft
Molecular Function
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
Type 2A Serotonin Receptor Binding
Metal Ion Binding
Endothelin Receptor Activity
Protein Binding
Peptide Hormone Binding
Type 1 Angiotensin Receptor Binding
Biological Process
Skeletal System Development
Action Potential
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Heart Development
Phototransduction, Visible Light
Entrainment Of Circadian Clock
Platelet Activation
Regulation Of Melanocyte Differentiation
Developmental Pigmentation
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Cellular Response To PH
Negative Regulation Of Transcription By RNA Polymerase II
Neural Crest Cell Migration
Positive Regulation Of Protein Phosphorylation
Regulation Of PH
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Nervous System Development
Peripheral Nervous System Development
Posterior Midgut Development
Aging
Regulation Of Blood Pressure
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Neuron Maturation
Response To Organic Cyclic Compound
Vein Smooth Muscle Contraction
Sensory Perception Of Pain
Calcium-mediated Signaling
CGMP-mediated Signaling
Melanocyte Differentiation
Regulation Of Fever Generation
Negative Regulation Of Cellular Protein Metabolic Process
Enteric Smooth Muscle Cell Differentiation
Positive Regulation Of Urine Volume
Positive Regulation Of Renal Sodium Excretion
Epithelial Fluid Transport
Vasoconstriction
Vasodilation
Negative Regulation Of Apoptotic Process
Macrophage Chemotaxis
Response To Pain
Enteric Nervous System Development
Regulation Of Epithelial Cell Proliferation
Regulation Of Sensory Perception Of Pain
Positive Regulation Of Penile Erection
Cellular Response To Lipopolysaccharide
Endothelin Receptor Signaling Pathway
Response To Endothelin
Pathways
Acetylcholine regulates insulin secretion
Acetylcholine regulates insulin secretion
G alpha (q) signalling events
G alpha (q) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
Thromboxane signalling through TP receptor
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Thrombin signalling through proteinase activated receptors (PARs)
Peptide ligand-binding receptors
G alpha (q) signalling events
Drugs
Bosentan
IRL-1620
Sitaxentan
Ambrisentan
Enrasentan
Tezosentan
Macitentan
Diseases
Hirschsprung disease (HD)
ABCD syndrome
Nasopharyngeal cancer
Waardenburg syndrome (WS)
GWAS
Asthma (
31959851
)
Craniofacial microsomia (
26853712
)
Hair color (
23548203
29662168
)
Total ventricular volume (Alzheimer's disease interaction) (
21116278
)
Interacting Genes
17 interacting genes:
ADRA1B
ADRB2
BDKRB2
CHRM2
EDNRA
EDNRB
HTR2A
HTR2B
KDR
MTNR1A
PTGIR
RGS14
RGS3
SLC9A3R1
TBXA2R
TRPC3
TSHR
7 interacting genes:
CAV1
EDN1
EDN3
GNA11
GNA13
GRK6
NOS3
Entrez ID
2767
1910
HPRD ID
00759
08834
Ensembl ID
ENSG00000088256
ENSG00000136160
Uniprot IDs
P29992
A0A024R638
A0A024R645
P24530
PDB IDs
6OIJ
5GLH
5GLI
5X93
5XPR
6IGK
6IGL
6LRY
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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