GLUL and TAT

Data Source:
BioGRID (two hybrid)

		GLUL	TAT
Description		glutamate-ammonia ligase	tyrosine aminotransferase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Extracellular Exosome	Cellular_component Mitochondrion Cytosol
	Molecular Function	Glutamate-ammonia Ligase Activity Protein Binding ATP Binding Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding Metal Ion Binding	L-tyrosine:2-oxoglutarate Aminotransferase Activity Protein Binding Amino Acid Binding Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Neurotransmitter Uptake Angiogenesis Glutamate Catabolic Process Glutamine Biosynthetic Process Cell Population Proliferation Cellular Amino Acid Biosynthetic Process Regulation Of Endothelial Cell Migration Protein Phosphopantetheinylation Protein Palmitoylation Ribosome Biogenesis Regulation Of Sprouting Angiogenesis Regulation Of Protein Localization To Nucleolus	2-oxoglutarate Metabolic Process Glutamate Metabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Response To Oxidative Stress Biosynthetic Process Response To Mercury Ion Response To Glucocorticoid
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate and glutamine metabolism	Tyrosine catabolism
Drugs		L-Glutamine Glutamic acid	Pyridoxal phosphate Phenylalanine Tyrosine Glutamic acid
Diseases		Congenital systemic glutamine deficiency (CSGD); Glutamine synthetase deficiency	Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS		Cardiovascular heart disease in diabetics ( 23982368) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol levels ( 32203549) Morning person ( 30696823)	Chronotype ( 30696823) Metabolite levels ( 22286219 22916037) Morning person ( 30696823) Urate levels ( 31578528)
Interacting Genes		22 interacting genes: CASP8AP2 CRBN CYP39A1 DYNLL1 EP300 HIPK1 HIPK3 HSD17B10 HTR2A MT-ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL TAT UBE2I	3 interacting genes: GLUL GRN UBE3A
Entrez ID		2752	6898
HPRD ID		00701	11776
Ensembl ID		ENSG00000135821	ENSG00000198650
Uniprot IDs		A8YXX4 P15104	A0A140VKB7 P17735
PDB IDs		2OJW 2QC8	3DYD
Enriched GO Terms of Interacting Partners?
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