BIN1 and RIN2

  • Data Source:
  • HPRD (in vitro)

BIN1

RIN2

Description bridging integrator 1 Ras and Rab interactor 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder and schizophrenia ( 20889312)
  • Bone mineral density (total hip) ( 29883787)
  • Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398)
  • HDL cholesterol ( 31170924)
  • Metabolite levels ( 23823483)
  • Obesity-related traits ( 23251661)
  • Platelet distribution width ( 32888494 27863252)
  • Response to valproic acid in genetic generalized epilepsy ( 32308125)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Trunk fat mass adjusted for trunk lean mass ( 32239398)
  • Verbal declarative memory ( 25648963)
  • Weight ( 28552196)
Interacting Genes 46 interacting genes: ABL1 ACTA1 ACTG1 AMPH AP2A1 AP2A2 APP APPL1 ASAP2 ATXN2 CLIP1 CUX1 DLGAP4 DNM1 DNM2 E2F1 FBP1 FHL2 ITCH ITGA1 ITGA3 ITGA6 MAP4K3 MBNL1 MYC PLD1 PLD2 PTGER4 PTK2 RAP1A RFX3 RIN2 RIN3 SH3GL2 SH3GLB1 SNAPIN SNX4 SOS1 SOS2 SYN1 SYNJ1 TP73 UBC WASL XRCC4 ZBTB3 7 interacting genes: BIN1 CDKN2A EGFR ERBB2 RAB5A RAB5B RAB5C
Entrez ID 274 54453
HPRD ID 03150 15249
Ensembl ID ENSG00000136717 ENSG00000132669
Uniprot IDs A0A024RAE9 A0A024RAF0 A0A024RAF1 A0A024RAF6 A0A024RAG8 A0A024RAG9 A0A024RAI4 A0A024RAI5 A0A024RAI6 A0A024RAJ2 A0A024RAJ3 B7Z2Z2 B7Z6Y2 O00499 Q9BTH3 A1A4T0 Q8WYP3
PDB IDs 1MUZ 1MV0 1MV3 2FIC 2RMY 2RND 5I22
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?