BMP10 and KIR3DL1

Data Source:
BioGRID (two hybrid)

		BMP10	KIR3DL1
Description		bone morphogenetic protein 10	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity
	Biological Process	Kidney Development Cell Adhesion Adult Heart Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis	Immune Response Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		Signaling by BMP Molecules associated with elastic fibres	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		59 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35C2 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR	6 interacting genes: BMP10 CDK3 HLA-B RPS6KB1 SMCO4 THSD7B
Entrez ID		27302	3811
HPRD ID		09788	09226
Ensembl ID		ENSG00000163217	ENSG00000167633
Uniprot IDs		O95393	P43629 Q5UCE2 Q6H2G3 Q8N6C9
PDB IDs		6SF1 6SF3	3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J
Enriched GO Terms of Interacting Partners?
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