RNF115 and CD160

Data Source:
BioGRID (affinity chromatography technology)

		RNF115	CD160
Description		ring finger protein 115	CD160 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Plasma Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity
	Biological Process	Protein Polyubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination	Angiogenesis Adaptive Immune Response Mucosal Immune Response Positive Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Interferon-gamma Production Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Breast cancer ( 25751625 29059683) HDL cholesterol levels ( 32203549) Platelet distribution width ( 32888494)	Diastolic blood pressure ( 30224653)
Interacting Genes		32 interacting genes: AKT1 APP ATN1 CDK10 CST3 DAZAP2 DOCK4 EGFR FOLR3 HRAS IGHA1 MDM4 MFAP4 NFKBIA RAB7A RAD23A RPL18A TTR UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2N UBE2W USP9X VCP ZNRD2	8 interacting genes: AGTRAP CMTM5 CMTM6 MAL2 MDM4 SYP THRA TNFRSF14
Entrez ID		27246	11126
HPRD ID		18328	06833
Ensembl ID		ENSG00000265491	ENSG00000117281
Uniprot IDs		Q9Y4L5	O95971 Q6FH89
PDB IDs			6NG3 6NG9 6NGG
Enriched GO Terms of Interacting Partners?
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