TRAPPC3 and TRAPPC6A

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRAPPC3	TRAPPC6A
Description		trafficking protein particle complex subunit 3	trafficking protein particle complex subunit 6A
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Cis-Golgi Network Membrane	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport COPII Vesicle Coating	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		Palmitic Acid Myristic acid S-palmitoyl-L-cysteine	S-palmitoyl-L-cysteine
Diseases
GWAS		Intraocular pressure ( 30054594)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		10 interacting genes: APP CDC45 LIG4 PLEKHF2 TRAPPC1 TRAPPC2 TRAPPC2B TRAPPC2L TRAPPC5 TRAPPC6A	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		27095	79090
HPRD ID		11644	14503
Ensembl ID		ENSG00000054116	ENSG00000007255
Uniprot IDs		A0A087WWM0 A0A087WYS5 O43617	B7TZ90 O75865
PDB IDs		1SZ7 2C0J 2CFH 3KXC	2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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