TRAPPC6A and PRR22

		TRAPPC6A	PRR22
Description		trafficking protein particle complex subunit 6A	proline rich 22
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	26 interacting genes: CDC23 COX5B CREB5 CRYBA2 CRYBA4 CYSRT1 DOK6 FOXH1 GPS2 GRB2 HGS HNRNPF KCTD7 KRTAP26-1 MKRN3 NELFA OTX1 PATZ1 PPIL1 SMYD1 SNRPB TFAP2D TNS2 TRAPPC6A UFSP1 VGLL3
Entrez ID		79090	163154
HPRD ID		14503	14501
Ensembl ID		ENSG00000007255	ENSG00000212123
Uniprot IDs		B7TZ90 O75865	Q8IZ63
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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