NSG1 and CISD2

Data Source:
BioGRID (two hybrid)

		NSG1	CISD2
Description		neuronal vesicle trafficking associated 1	CDGSH iron sulfur domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Lateral Plasma Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Somatodendritic Compartment Lysosomal Lumen Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Endosome Glutamatergic Synapse	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Signaling Receptor Binding Protein Binding Clathrin Light Chain Binding	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Receptor Recycling Positive Regulation Of Receptor Recycling Apoptotic Process Dopamine Receptor Signaling Pathway Endosomal Transport Amyloid Precursor Protein Metabolic Process Clathrin Coat Assembly Spontaneous Synaptic Transmission Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Neurotransmitter Receptor Cycle Postsynaptic Neurotransmitter Receptor Cycle Regulation Of Long-term Synaptic Potentiation	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways
Drugs
Diseases			Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS			Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		32 interacting genes: ATP6AP2 BSCL2 BTN2A1 C16orf92 CISD2 CREB3L1 CYB5R3 ERGIC3 EVI2B FCGR2A FFAR2 FNDC9 GPA33 GPR42 KASH5 KIR2DL3 MGST3 OPRM1 PDZK1IP1 PLPP2 RELL2 SLC23A2 SLC30A4 SLC7A14 SPACA1 STX12 TM4SF18 TMEM139 TMEM207 TMEM45B TMEM52B TMX2	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		27065	493856
HPRD ID		09624	17413
Ensembl ID		ENSG00000168824	ENSG00000145354
Uniprot IDs		B2R5R8 P42857	Q8N5K1
PDB IDs			3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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