NSG1 and ATP6AP2

Data Source:
BioGRID (two hybrid)

		NSG1	ATP6AP2
Description		neuronal vesicle trafficking associated 1	ATPase H+ transporting accessory protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Lateral Plasma Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Golgi Cisterna Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Somatodendritic Compartment Lysosomal Lumen Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Endosome Glutamatergic Synapse	Autophagosome Membrane Lysosome Lysosomal Membrane Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Axon Dendritic Spine Membrane Cell Body Postsynaptic Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Clathrin Light Chain Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Receptor Recycling Positive Regulation Of Receptor Recycling Apoptotic Process Dopamine Receptor Signaling Pathway Endosomal Transport Amyloid Precursor Protein Metabolic Process Clathrin Coat Assembly Spontaneous Synaptic Transmission Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Neurotransmitter Receptor Cycle Postsynaptic Neurotransmitter Receptor Cycle Regulation Of Long-term Synaptic Potentiation	Angiotensin Maturation Lysosomal Lumen Acidification Central Nervous System Maturation Rostrocaudal Neural Tube Patterning Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta1 Production Neutrophil Degranulation Regulation Of MAPK Cascade Eye Pigmentation Head Morphogenesis Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS			Metabolite levels ( 23823483)
Interacting Genes		32 interacting genes: ATP6AP2 BSCL2 BTN2A1 C16orf92 CISD2 CREB3L1 CYB5R3 ERGIC3 EVI2B FCGR2A FFAR2 FNDC9 GPA33 GPR42 KASH5 KIR2DL3 MGST3 OPRM1 PDZK1IP1 PLPP2 RELL2 SLC23A2 SLC30A4 SLC7A14 SPACA1 STX12 TM4SF18 TMEM139 TMEM207 TMEM45B TMEM52B TMX2	19 interacting genes: ADRA1A AGT CD72 CREB3 GLP1R HTR2C NKG7 NSG1 PMP22 PTTG1IP REN SEC22A TIMMDC1 TMEM203 TMEM97 UPK2 VAMP5 VKORC1 ZBTB16
Entrez ID		27065	10159
HPRD ID		09624	06454
Ensembl ID		ENSG00000168824	ENSG00000182220
Uniprot IDs		B2R5R8 P42857	O75787
PDB IDs			3LBS 3LC8
Enriched GO Terms of Interacting Partners?
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