ANKRD2 and TCAP

Data Source:
HPRD (in vitro, in vivo)

		ANKRD2	TCAP
Description		ankyrin repeat domain 2	titin-cap
Image		No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Cytosol PML Body I Band Intracellular Membrane-bounded Organelle	Cytosol Z Disc I Band
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Kinase B Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding Structural Constituent Of Muscle Protein-macromolecule Adaptor Activity Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Contraction Muscle Organ Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Myoblast Differentiation	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly
Pathways			Striated Muscle Contraction
Drugs
Diseases			Limb-girdle muscular dystrophy (LGMD)
GWAS			Alcohol consumption ( 31358974) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		11 interacting genes: FCMR HBP1 HOMEZ LDB3 MAPK6 PML TCAP TP53 TTN YBX1 ZBTB3	38 interacting genes: ADPGK ANKRD2 ASB6 ATXN1 BLZF1 C19orf54 CDCA4 CHORDC1 CRK ENO1 ENO3 FAM153B FAS FYN HSPA8 HSPB2 HSPB3 HSPG2 IKZF3 KLHL41 KRTAP19-7 LAMTOR5 LHX4 MDM2 MSTN MYOZ1 MYOZ3 NUP133 PAX7 PDPK1 RELA SAPCD1 SIVA1 TRIM54 TRIM55 TRIM63 TTC19 TTN
Entrez ID		26287	8557
HPRD ID		12460	05133
Ensembl ID		ENSG00000165887	ENSG00000173991
Uniprot IDs		A0A0A0MRN9 Q5T457 Q9GZV1	A2TDC0 O15273
PDB IDs			1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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