ANKRD2 and LDB3

Data Source:
BioGRID (far western blotting)

		ANKRD2	LDB3
Description		ankyrin repeat domain 2	LIM domain binding 3
Image		No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Cytosol PML Body I Band Intracellular Membrane-bounded Organelle	Stress Fiber Cytoskeleton Adherens Junction Z Disc Pseudopodium Filamentous Actin Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Kinase B Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Actin Binding Protein Kinase C Binding Protein Binding Cytoskeletal Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Contraction Muscle Organ Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Myoblast Differentiation	Heart Development Actin Cytoskeleton Organization Sarcomere Organization Muscle Structure Development
Pathways
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		11 interacting genes: FCMR HBP1 HOMEZ LDB3 MAPK6 PML TCAP TP53 TTN YBX1 ZBTB3	7 interacting genes: ACTN2 ANKRD2 MYOZ1 MYOZ2 MYOZ3 TFCP2 TP53
Entrez ID		26287	11155
HPRD ID		12460	16172
Ensembl ID		ENSG00000165887	ENSG00000122367
Uniprot IDs		A0A0A0MRN9 Q5T457 Q9GZV1	A0A0S2Z501 A0A0S2Z530 O75112
PDB IDs			1RGW 4YDP
Enriched GO Terms of Interacting Partners?
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