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TINF2 and RPSA
Data Source:
BioGRID
(two hybrid)
TINF2
RPSA
Description
TERF1 interacting nuclear factor 2
ribosomal protein SA
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleoplasm
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Cytosolic Small Ribosomal Subunit
Extracellular Exosome
Molecular Function
DNA Binding
Protein Binding
Telomeric DNA Binding
Virus Receptor Activity
RNA Binding
Structural Constituent Of Ribosome
Laminin Receptor Activity
Protein Binding
Ribosome Binding
Laminin Binding
Biological Process
Negative Regulation Of Protein ADP-ribosylation
Telomere Capping
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Ribosomal Small Subunit Assembly
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cytoplasmic Translation
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Cell Adhesion
Viral Transcription
Viral Entry Into Host Cell
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Tigapotide
Copper
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
GWAS
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
Dentate gyrus volume x schizophrenia interaction (
31155012
)
Interacting Genes
89 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
31 interacting genes:
ABCD1
ACADVL
ACD
ANKH
CALM2
CBX5
CCDC13
CLEC4G
CSF2RA
DCTN6
GNMT
HBG2
HNRNPD
HSPB1
IL7R
ILRUN
ITGA6
KARS1
LAMA2
LINC01554
NKX3-1
PEA15
POT1
PRND
PROS1
RNF114
RPS21
SLC2A5
SUMO4
TINF2
TRIB3
Entrez ID
26277
3921
HPRD ID
16056
01038
Ensembl ID
ENSG00000092330
ENSG00000168028
Uniprot IDs
Q9BSI4
A0A024R2L6
A0A0C4DG17
P08865
PDB IDs
3BQO
3BU8
5XYF
3BCH
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6EK0
6FEC
6G18
6G4S
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBD
6YBW
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOK
6ZON
6ZP4
6ZVH
6ZVJ
7A09
7K5I
Enriched GO Terms of Interacting Partners
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