GAP43 and RABEP1

Data Source:
HPRD (in vivo, in vitro)

		GAP43	RABEP1
Description		growth associated protein 43	rabaptin, RAB GTPase binding effector protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Dendrite Filopodium Membrane Growth Cone Membrane Perikaryon GABA-ergic Synapse	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Phosphatidylserine Binding Protein Binding Calmodulin Binding Lysophosphatidic Acid Binding Phosphatidylinositol Phosphate Binding	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Axon Regeneration Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Regulation Of Postsynaptic Specialization Assembly	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane
Pathways		L1CAM interactions	TBC/RABGAPs
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) Breast size ( 22747683) Metabolite levels ( 23823483) Proliferative diabetic retinopathy ( 31482010) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Seasonality and depression ( 30217971) Urate levels in obese individuals ( 25811787)	Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		8 interacting genes: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1	58 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		2596	9135
HPRD ID		01198	04684
Ensembl ID		ENSG00000172020	ENSG00000029725
Uniprot IDs		P17677 Q5U058	B4DMM4 Q15276
PDB IDs			1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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