RABEP1 and RAB33B

Data Source:
HPRD (in vivo, in vitro)

		RABEP1	RAB33B
Description		rabaptin, RAB GTPase binding effector protein 1	RAB33B, member RAS oncogene family
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GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Golgi Membrane Endosome Golgi Apparatus Golgi Lumen
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane	Regulation Of Cell Growth Intra-Golgi Vesicle-mediated Transport Autophagy Protein Transport Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Skeletal System Morphogenesis Regulation Of Epithelial Cell Proliferation Regulation Of Golgi Organization Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER
Pathways		TBC/RABGAPs	Intra-Golgi traffic TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		58 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774	12 interacting genes: ACVR1 ATG16L1 ATG16L2 ATG5 CCDC136 GOLGA2 RABEP1 RABGEF1 RUFY2 SIAH1 TGFBR1 USP6
Entrez ID		9135	83452
HPRD ID		04684	05808
Ensembl ID		ENSG00000029725	ENSG00000172007
Uniprot IDs		B4DMM4 Q15276	A0A494C0Z5 Q9H082
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U	6Y09 6ZAY
Enriched GO Terms of Interacting Partners?
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