GABRR1 and MAP1B

Data Source:
HPRD (in vivo)

		GABRR1	MAP1B
Description		gamma-aminobutyric acid type A receptor subunit rho1	microtubule associated protein 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glutamatergic Synapse GABA-ergic Synapse GABA-A Receptor Complex	Photoreceptor Outer Segment Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Postsynaptic Density Axon Dendrite Growth Cone Somatodendritic Compartment Neuronal Cell Body Varicosity Dendritic Spine Perikaryon Synapse Perinuclear Region Of Cytoplasm Apical Dendrite Basal Dendrite Hippocampal Mossy Fiber
	Molecular Function	GABA-A Receptor Activity Chloride Channel Activity Neurotransmitter Receptor Activity Ligand-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Actin Binding Structural Molecule Activity Protein Binding Phospholipid Binding Microtubule Binding Protein-containing Complex Binding
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Regulation Of Postsynaptic Membrane Potential Regulation Of Presynaptic Membrane Potential Chloride Transmembrane Transport	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Neuron Migration Negative Regulation Of Microtubule Depolymerization Axonogenesis Synapse Assembly Response To Mechanical Stimulus Response To Carbohydrate Cellular Process Response To Inorganic Substance Peripheral Nervous System Axon Regeneration Dendrite Development Response To Insecticide Developmental Maturation Regulation Of Microtubule Depolymerization Positive Regulation Of Microtubule Polymerization Response To Estradiol Negative Regulation Of Intracellular Transport Response To Vitamin A Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Mitochondrion Transport Along Microtubule Axon Extension Induction Of Synaptic Plasticity By Chemical Substance Establishment Of Monopolar Cell Polarity Cellular Response To Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus
Pathways		GABA receptor activation
Drugs		Lindane Picrotoxin Fludiazepam
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder and schizophrenia ( 20889312) Diabetic kidney disease in type 2 diabetes ( 29703844) Early diabetic kidney disease in type 2 diabetes ( 29703844) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)	Attention deficit hyperactivity disorder ( 18839057) Coronary artery disease in type 1 diabetes ( 29695241) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: CSNK2A1 GABRR2 MAP1B MAPK1 P2RX2 PRKACA PRKCA PRKG1 SLC6A9 SQSTM1	29 interacting genes: ACTB ANP32A ARHGEF11 DYNLL1 EEF1D ERBB3 FOS GABRR1 GABRR2 GAN GSK3B HTR6 LRRK2 MAG MAGOH MAP1A MAPK8 MARCHF5 MINK1 NXF1 NXF2 PAFAH1B1 RASSF1 SNCA SPP1 STAU1 STRAP U2AF1 U2AF2
Entrez ID		2569	4131
HPRD ID		15921	01139
Ensembl ID		ENSG00000146276	ENSG00000131711
Uniprot IDs		P24046	A2BDK6 P46821 Q6PJD3 Q86X89
PDB IDs
Enriched GO Terms of Interacting Partners?
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