APOL2 and USE1

Data Source:
BioGRID (two hybrid)

		APOL2	USE1
Description		apolipoprotein L2	unconventional SNARE in the ER 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Membrane	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle SNARE Complex
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	SNAP Receptor Activity Protein Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Multicellular Organism Development Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Lysosomal Transport Protein Transport Protein Catabolic Process Secretion By Cell Membrane Fusion
Pathways			COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		33 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 EMP1 FAM209A GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 STX1A STX2 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	18 interacting genes: APOL2 APP AQP6 BSCL2 CALN1 CCDC70 CCM2L CREB3 EBP JAGN1 LMNA MEOX2 MFSD14B SCN3B STX1A STX4 TMEM86B TRIM27
Entrez ID		23780	55850
HPRD ID		06263	11299
Ensembl ID		ENSG00000128335	ENSG00000053501
Uniprot IDs		A0A024R1M8 J3KQL8 Q9BQE5	Q9NZ43
PDB IDs
Enriched GO Terms of Interacting Partners?
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