APOL2 and SIT1

Data Source:
BioGRID (two hybrid)

		APOL2	SIT1
Description		apolipoprotein L2	signaling threshold regulating transmembrane adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding	Protein Binding Kinase Binding SH2 Domain Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Acute-phase Response Multicellular Organism Development Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy	Adaptive Immune Response Signal Transduction T Cell Homeostasis Regulation Of T Cell Activation
Pathways
Drugs
Diseases
GWAS		Epigenetic age acceleration in alcohol use disorder ( 31466081)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Interacting Genes		33 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 EMP1 FAM209A GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 STX1A STX2 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6	17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70
Entrez ID		23780	27240
HPRD ID		06263	05394
Ensembl ID		ENSG00000128335	ENSG00000137078
Uniprot IDs		A0A024R1M8 J3KQL8 Q9BQE5	Q9Y3P8
PDB IDs
Enriched GO Terms of Interacting Partners?
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