GABARAPL1 and OPRK1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		GABARAPL1	OPRK1
Description		GABA type A receptor associated protein like 1	opioid receptor kappa 1
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GO Annotations	Cellular Component	Autophagosome Membrane Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Synapse
	Molecular Function	Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	G Protein-coupled Receptor Activity Opioid Receptor Activity Protein Binding Dynorphin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation	Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Sensory Perception Locomotory Behavior Sensory Perception Of Pain Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Opioid Receptor Signaling Pathway Regulation Of Saliva Secretion Defense Response To Virus
Pathways		Macroautophagy	Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates neuronal receptors and channels
Drugs			Tramadol Atomoxetine Morphine Codeine Amitriptyline Hydromorphone Mirtazapine Progesterone Meperidine Oxycodone Dextromethorphan Lamotrigine Butorphanol Dextropropoxyphene Pentazocine Naltrexone Sufentanil Fentanyl Levomenthol Loperamide Nalbuphine Levorphanol Remifentanil Buprenorphine Naloxone Dezocine Ketamine Aripiprazole 3-Methylthiofentanyl Diamorphine Etorphine Carfentanil Diprenorphine Dihydromorphine 3-Methylfentanyl V1003 Asimadoline CR665 ADL 10-0101 Mianserin Tapentadol Nalmefene Alvimopan Morphine glucuronide Ketobemidone Methylnaltrexone Butyrfentanyl Pholcodine Eluxadoline Opium Pentoxyverine Naldemedine Loxicodegol
Diseases
GWAS			Body size at age 10 ( 32376654) IgE levels in asthmatics (D.p. specific) ( 23967269) Modic changes ( 30808802) Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373)
Interacting Genes		73 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4B ATG4D BNIP3L BSCL2 BSDC1 CALCOCO1 CALCOCO2 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 HSP90AA1 HSP90AB1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV MLX NEDD4 NFIA OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM32 ULK1 UMAD1 VDR WDFY3 ZBTB22	6 interacting genes: GABARAPL1 GNA15 GPRASP1 NKG7 OPRD1 SLC9A3R1
Entrez ID		23710	4986
HPRD ID		07601	01309
Ensembl ID		ENSG00000139112	ENSG00000082556
Uniprot IDs		A0A024RAP5 Q9H0R8	A0A5F9ZI09 P41145
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL	2A0D 2IQN 4DJH 6B73 6VI4
Enriched GO Terms of Interacting Partners?
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